Gotoh sp vs psp6/14/2023 Accuracy is measured using four benchmarks: BAliBASE, PREFAB, SABmark and SMART. We compare the speed and accuracy of MUSCLE with CLUSTALW, Progressive POA and the MAFFT script FFTNS1, the fastest previously published program known to the author. We also describe a new protocol for evaluating objective functions that align two profiles. We introduce a new option, MUSCLE-fast, designed for high-throughput applications. ![]() ![]() Here we present a more complete discussion of the algorithm, describing several previously unpublished techniques that improve biological accuracy and / or computational complexity. ![]() In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUSCLE to achieve the highest scores reported to date on four alignment accuracy benchmarks.
0 Comments
Leave a Reply. |